Zoom is not designed to work with multichannel audio, so on macOS, it will generally pick up and/or send to the first two USB channels in each direction.
With Windows, you can use one of the 4 stereo WDM (Windows system) devices provided by the driver – these use the first 4 pairs of USB channels as labelled, so input device ‘SQ 1&2’ is whatever you’ve patched to USB 1&2 from the SQ, then playback device ‘SQ 1&2’ will go back out to the SQ and appear as USB-B input channels 1&2.
If you need more help with this, please contact us using https://support.allen-heath.com
Cheers!
Keith.