We have it up and running ok, using two separate stereo channels for the desk.
(we use separate worship group and lectern/speaker feeds as the noise cancellation is very useful for the speakers, but definitely not for the music).
It works nicely as long as you add about 20 – 24dB gain to the input on OBS.
We had some issues with getting an output back to our desk for video inserts etc. but found the Audio Monitor plugin very useful for this purposes.
Using the USB input helped cut down on the cabling (originally we used a Focusrite interface).