Hi Rsaudio,
The iDR48 is the mixer, so you would be connecting two different systems.
This would only be possible using Dante, and you would have no control over the iLive system from the SQ system.
So I would suggest this is not an ideal setup.
As far as whether to go for SQ or iLive, it depends on what you need.
As a starting point though:
SQ = 48 channel, 96kHz XCVI core, low latency, DEEP processing ready, SQ-Drive and USB-B, compact with local preamps and lots of expansion options.
iLive = 64 channel, 48kHz, more configurable busses, split mixrack/surface setup, offline PC editor.
Cheers,
Keith.