@Aaronious
When a line or digital input is the source for an input channel there is no preamp to control and so the trim is shown in place of the gain knob on the channel strip.
Preamp gain control has a red surround.
Digital trim has a blue surround.
If this doesn’t explain what you’re seeing, please contact us using support.allen-heath.com and if possible include a quick video of the behaviour.
You can definitely use the USB-B connection to a Mac with no issue, so there must be something going on with the settings somewhere!
Thanks,
Keith.