@ABKK if it was only when playing it back, and because you mention loosing low end, I would recommend checking that you do not have a phase issue somewhere.
This could be caused in the desk by doing something like playing back the same source on multiple channels with polarity inversion or extra latency on one of those channels.
There are also stereo options on input channels that could cause problems if used incorrectly.
In the analogue domain, and as you mention using IEM’s, ensure that you are not using balanced outputs to feed stereo inputs (though issues with this should be apparent instantly rather than after a couple of hours!).
Thanks,
Keith.