I’d probably use a ADAT-DAC and record all channels only through one interface, otherwise someone (probably the mac in this case) needs to consolidate samplingrates (=resampling). This is obvious if your recordings are 44.1kHz and the Qu only supports 48kHz, but also happens with recordings at 48kHz, since both units are not sample synchronized.
In any case I expect that you need to align the recorded tracks afterwards, since the conversion latency through the Qu will differ from the latency through the digital path. We’re talking about a few mSec here. Not really audible but enough to potentially cause phase issues if different paths carry signals from same audio source.