Same question for traditional line instruments…
what are traditional line instruments?
Mostly the are no line instruments, they send very low signal and need to see high impedance inputs…
a DI box is exactly made for this kind of signal… e-Pianos, guitar amps, synthies
it changes the impedance and makes the signal symmetrical for longer hum and buzz free cable runs
bring the DI box close to the instrument and you will have solved 80% of your humming and buzzing problems