I’d first rule out the multicore and connect the laptop (and possibly mic) directly to the mixer on same channel(s). If this fixes your issue, I’d check if using a another multicore socket helps. If it does help, check for a broken cable. If switching multicore socket doesn’t help, try a different DI box (you hopefully do use a proper DI?). If you do not use a DI for the laptop, use a DI.
If bleeding persists with mic and laptop directly connected to the mixer, then check the internal routings as described above.