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On the PC try changing your video card. For whatever reason, I could not get the distortion/artifacts to stop (and they occurred after about 15 mins then started after about 5). I’ve got a QU-24, PC with AMD based motherboard. I changed the usb cable, reformated windows, got rid of my ssd, went to ever known firmware, even bought new DAWs, in the end it turned out to be the VIDEO CARD. For me, no NVIDIA based card would work, only ATI/AMD. Now at 7ms latency (couldn’t even go less than 2048 samples before) Samplitude complains of a drop asio buffer rarely and I’ve never had the glitches before.
Hope this helps.. good luck.