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I think this is a misunderstanding of the ME-1 units. You send audio to the devices rather than using them as a control surface.

So, you can send an AUX as a channel to the ME-1s but the audio output is then at the ME-1 rather than from the GLD.

So yes if you have unpowered wedges…

Output from GLD (direct outs etc) -> ME-1 -> Output to amp -> wedge

The best use for them is going to be with IEMs (headphones) or powered wedges. But with wedges you will need to be careful so that musicians don’t give themselves too much “me” ;-)