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on the R72 I used them for mute group masters,individual input channel EQs and compressors and soon as midi “go” message to my Qlab/Cricket rig, of course tap is a good one too…..from the pdf manual.:

For example, you could
use them as MUTE GROUP masters, to recall Scene memories,
quickly access processing or mix parameters of a certain channel or
master, send a MIDI message and more.The master Mutes can be
operated using the Soft Keys giving you instant access to control your
eight Mute groups.